The “human search”(a Chinese term for the phenomenon of distributed searching of a man’s information by using Internet media through blogs and many other forums) technology of the Internet era is often a powerful tool to entertain the public, but unfortunately, it can also become a tool causing unfortunate.

The story begins with an incident that happened on a bus, Ye Lanqiu (Yuanyuan Gao), secretary to the chairman of a listed company is informed that she has cancer. In a state of shock and fear, she refuses to give up her seat for an old man, causing a public debate. The news on the bus is quickly handed over to her sister-in-law Chen Ruoxi (Chen Yao), who, with the keen sense of a news editor-in-chief, amplifies the news maliciously, triggering a social search and a collective crusade against Ye Lanqiu’s moral degradation. In the midst of the public accusations and the illness, Ye Lanqiu disappears with the 1 million Yuan loaned to her by her boss Shen Liushu (Xueqi Wang). She was not expecting to be branded as a “mistress”. Chen Ruoxi’s boyfriend is inadvertently drawn into Ye Lanqiu’s world and hired to accompany her for a good paycheck. But he never expected that this would be the last time in the life of this much-accused woman. Ye Lanqiu’s suicide completely turns Chen Ruoxi’s love and life upside down and makes everyone start to reflect on ……

        网络时代的“人肉”技术，通常是娱乐大众的利器，但很不幸，它也可能成为一种杀人工具。
　    上市企业董事长秘书叶蓝秋（高圆圆 饰）在获知自己罹患癌症之后，心灰意冷的她上了一辆公交车，沉浸在惊愕与恐惧的她，拒绝给车上的老大爷让座，引起众议，这一过程被电视台实习记者杨佳琪（王珞丹 饰）用手机拍个正着。佳琪将公车上的新闻火速交给准嫂子陈若兮（姚晨 饰），凭着新闻主编的敏锐嗅觉，若兮将此新闻恶意放大，从而引发了一场社会大搜索，集体讨伐叶蓝秋的道德沦丧。在公众指责和病魔降临的夹缝中，叶蓝秋带着老板沈流舒（王学圻 饰）借给她的100万，彻底玩起了消失。岂料这更使她被冠以“小三”之名。若兮的摄影师男友无意中被卷入叶蓝秋的世界中，为了获得一笔高额报酬，他受雇陪伴在叶左右。而他却不曾想到，这竟是这个饱受指责的女人生命中最后一段时光。叶蓝秋的自杀，彻底颠覆了陈若兮的爱情与生活，也让所有人开始反思……